|
| 13:30 Sanfrecce Hiroshima – Shanghai Shenhua 1:0 | 1.31 | 5.57 | 9.65 | 1 | 2-1 | O | no |
| 13:30 Seoul – Melbourne City 1:1 | 1.84 | 3.64 | 4.35 | 1 | 2-0 | U | no |
|
| 16:30 Aluminium Arak – Sepahan Isfahan 0:1 | 4.96 | 2.89 | 1.81 | 2X | 0-2 | U | no |
| 16:30 Fajr Sepasi – Chador Malu 1:2 | 3.06 | 2.80 | 2.41 | 2X | 0-2 | U | no |
| 17:15 Esteghlal – Malavan 1:1 | 1.70 | 3.05 | 5.46 | 2X | 0-2 | U | no |
| 17:15 Mes Rafsanjan – Foolad Khuzestan 0:0 | 3.20 | 2.67 | 2.43 | 2X | 0-2 | U | no |
|
| 20:30 Stade Lausanne-Ouchy – Xamax 3:0 | 1.72 | 3.74 | 3.98 | 1 | 2-1 | O | yes |
|
| 21:15 Qarabag – Ajax 2:4 | 2.18 | 3.88 | 3.36 | 1X | 2-1 | O | no |
| 21:15 Villarreal – Copenhagen 2:3 | 1.52 | 4.93 | 6.55 | 1 | 2-1 | O | no |
|
| 22:30 Club Blooming – Club Aurora 2:1 | 1.43 | 4.60 | 5.47 | 1 | 3-1 | O | yes |
|
| 22:30 Vitesse – Waalwijk 2:1 | 2.60 | 3.70 | 2.36 | 2X | 1-2 | O | yes |
|
| 23:15 Bristol City – Leicester City 2:2 | 2.23 | 3.32 | 3.16 | 1X | 2-1 | U | no |
| 23:15 Derby County – Millwall 1:1 | 2.67 | 3.02 | 2.73 | 2X | 0-2 | U | no |
| 23:15 Ipswich Town – Stoke City 1:0 | 1.62 | 3.78 | 5.41 | 1 | 2-1 | U | no |
|
| 23:15 Rotherham United – Blackpool 0:3 | 2.38 | 3.20 | 2.99 | X2 | 0-1 | U | no |
|
| 23:15 Crewe Alexandra – Newport County 2:2 | 1.60 | 3.88 | 5.24 | X2 | 1-2 | U | no |
| 23:15 Oldham Athletic – Walsall 0:1 | 2.62 | 3.05 | 2.70 | 2X | 0-2 | U | no |
|
| 23:15 Carlisle United – Woking 1:3 | 1.47 | 3.98 | 5.96 | 1 | 2-1 | U | no |
|
| 23:30 Hull City – Wrexham 2:0 | 2.38 | 3.32 | 2.89 | 1X | 2-1 | U | no |
|
| 23:30 Athletic Bilbao – Paris Saint-Germain 0:0 | 5.08 | 4.02 | 1.76 | 2 | 0-3 | U | yes |
| 23:30 Bayer 04 Leverkusen – Newcastle United 2:2 | 3.13 | 3.76 | 2.33 | 1X | 2-1 | U | no |
| 23:30 Benfica – Napoli 2:0 | 2.61 | 3.19 | 3.13 | 1X | 2-1 | O | no |
| 23:30 Borussia Dortmund – Bodo-Glimt 2:2 | 1.32 | 6.15 | 10.40 | 1 | 3-1 | O | no |
| 23:30 Club Brugge – Arsenal 0:3 | 8.00 | 5.18 | 1.43 | 1X | 2-1 | O | no |
| 23:30 Juventus – Pafos 2:0 | 1.20 | 7.65 | 18.50 | 1 | 2-1 | O | no |
| 23:30 Real Madrid – Manchester City 1:2 | 2.92 | 3.94 | 2.38 | 1X | 3-0 | O | yes |
|
| 01:00 Universitario de Vinto – Independiente Petrolero 2:3 | 2.29 | 3.62 | 2.52 | X2 | 0-3 | U | no |
|
| 01:30 Independiente del Valle – Liga Deportiva Universitaria de Quito 0:0 | 2.46 | 3.10 | 2.93 | X2 | 0-1 | U | no |
