|
| 16:30 Malavan – Shams Azar Qazvin 0:0 | 2.19 | 2.74 | 3.60 | 1X | 2-0 | U | no |
| 17:30 Gol Gohar – Zob Ahan 1:2 | 2.20 | 2.61 | 3.82 | 2X | 0-2 | U | no |
|
| 18:25 Al Hazm Rass – Al-Khaleej 1:4 | 3.20 | 3.38 | 2.04 | 1X | 2-1 | U | no |
| 21:00 Al-Riyadh SC – Damac 1:1 | 2.13 | 3.14 | 3.20 | 1X | 2-1 | U | no |
| 21:00 Al-Qadisiyah – Al Kholood 4:0 | 1.42 | 4.30 | 6.16 | 1 | 2-1 | U | no |
|
| 21:15 1. FSV Mainz 05 – Fiorentina 2:1 | 2.24 | 3.31 | 3.41 | X2 | 1-2 | O | no |
| 21:15 AC Sparta Prague – Rakow Czestochowa 0:0 | 1.80 | 3.64 | 4.73 | 1 | 2-0 | U | yes |
| 21:15 AEK Athens – Shamrock Rovers 1:1 | 1.16 | 7.90 | 19.50 | 1 | 2-1 | O | no |
| 21:15 AEK Larnaca – Aberdeen 0:0 | 1.50 | 4.38 | 6.74 | 1 | 2-1 | U | no |
| 21:15 Celje – Legia Warsaw 2:1 | 2.38 | 3.54 | 2.96 | 1X | 1-0 | U | no |
| 21:15 Kuopion Palloseura – Slovan Bratislava 3:1 | 3.55 | 3.70 | 2.04 | X2 | 1-2 | U | yes |
| 21:15 Noah Yerevan – Sigma Olomouc 1:2 | 2.08 | 3.56 | 3.58 | 1X | 2-1 | U | no |
| 21:15 Samsunspor – Hamrun Spartans 3:0 | 1.20 | 7.27 | 14.30 | 1 | 2-1 | O | no |
| 21:15 Shakhtar Donetsk – Breidablik UBK 2:0 | 1.18 | 7.75 | 15.00 | 1 | 3-1 | O | no |
|
| 21:15 Basel – FCSB 3:1 | 1.59 | 4.50 | 6.14 | 1 | 2-1 | O | no |
| 21:15 Crvena Zvezda – Lille OSC 1:0 | 3.04 | 3.74 | 2.38 | 1X | 3-0 | U | no |
| 21:15 Dinamo Zagreb – Celta 0:3 | 2.74 | 3.56 | 2.70 | 1X | 2-1 | U | no |
| 21:15 FC Salzburg – Go Ahead Eagles 2:0 | 1.68 | 4.35 | 5.27 | 1 | 2-1 | O | no |
| 21:15 Malmo – Panathinaikos 0:1 | 2.80 | 3.48 | 2.70 | X2 | 0-3 | U | no |
| 21:15 Midtjylland – Celtic 3:1 | 2.14 | 3.86 | 3.46 | 1X | 2-1 | O | no |
| 21:15 Nice – Freiburg 1:3 | 2.74 | 3.46 | 2.76 | 1X | 2-1 | U | no |
| 21:15 Sturm Graz – Nottingham Forest 0:0 | 5.26 | 4.19 | 1.70 | 1X | 2-0 | U | yes |
| 21:15 Utrecht – Porto 1:1 | 5.21 | 4.14 | 1.72 | X2 | 1-2 | U | yes |
|
| 23:30 Reading – Stevenage 1:0 | 2.84 | 3.15 | 2.48 | 1X | 2-1 | U | no |
|
| 23:30 Crystal Palace – AZ Alkmaar 3:1 | 1.45 | 4.78 | 6.94 | 1 | 2-1 | O | no |
| 23:30 Dynamo Kyiv – Zrinjski 6:0 | 1.66 | 3.95 | 5.40 | 1 | 2-1 | U | no |
| 23:30 Hacken – Strasbourg 1:2 | 3.34 | 3.85 | 2.07 | 2X | 1-2 | O | no |
| 23:30 Lausanne-Sport – AC Omonia 1:1 | 2.18 | 3.60 | 3.27 | 1X | 2-1 | U | no |
| 23:30 Lincoln Red Imps – Rijeka 1:1 | 8.65 | 4.76 | 1.40 | 2 | 1-3 | U | yes |
| 23:30 Rapid Wien – CS Universitatea Craiova 0:1 | 1.80 | 3.72 | 4.58 | 1 | 2-0 | U | no |
| 23:30 Rayo Vallecano – Lech Poznan 3:2 | 1.51 | 4.46 | 6.38 | 1 | 2-1 | U | no |
| 23:30 Shelbourne – KF Drita 0:1 | 1.85 | 3.62 | 4.42 | 1 | 2-1 | O | no |
| 23:30 Skendija – Jagiellonia Bialystok 1:1 | 3.89 | 3.62 | 1.96 | X2 | 1-2 | U | yes |
|
| 23:30 Aston Villa – Maccabi Tel Aviv 2:0 | 1.24 | 6.89 | 15.00 | 1 | 2-1 | O | no |
| 23:30 Bologna 1909 – Brann 0:0 | 1.41 | 5.16 | 8.80 | 1 | 2-1 | O | no |
| 23:30 Braga – Genk 3:4 | 1.77 | 4.20 | 4.70 | 1 | 2-0 | U | no |
| 23:30 Ferencvarosi – Ludogorets 1945 3:1 | 1.69 | 4.20 | 5.42 | 1 | 2-1 | U | no |
| 23:30 P.A.O.K. – Young Boys 4:0 | 1.73 | 4.34 | 4.85 | 1 | 2-1 | O | yes |
| 23:30 Rangers – Roma 0:2 | 5.22 | 4.10 | 1.72 | X2 | 1-2 | O | yes |
| 23:30 Real Betis – Lyon 2:0 | 1.82 | 4.14 | 4.45 | 1 | 2-1 | O | no |
| 23:30 VfB Stuttgart – Feyenoord 2:0 | 1.79 | 4.14 | 4.65 | 1 | 2-1 | O | no |
| 23:30 Viktoria Plzen – Fenerbahce 0:0 | 3.22 | 3.66 | 2.31 | X2 | 1-2 | U | no |
|
| 02:00 Fluminense – Mirassol 1:0 | 1.92 | 3.38 | 4.42 | 2X | 0-2 | U | no |
|
| 02:30 Bolivar – Club Aurora 6:1 | 1.36 | 4.90 | 6.25 | 1 | 3-1 | O | no |
|
| 02:30 Ceara – Fortaleza EC 1:1 | 2.31 | 3.17 | 3.42 | 1X | 2-0 | U | no |
