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| 13:59 CSKA Moscow – Kuban Krasnodar : | | |
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| 14:59 Ajax – Feyenoord : | | |
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| 15:59 Dynamo Dresden – FSV Frankfurt : | | |
| 15:59 Energie Cottbus – VfR Aalen : | | |
| 15:59 TSV 1860 Munchen – Ingolstadt 04 : | | |
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| 16:29 AS Monaco – Montpellier : | | |
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| 16:59 NAC Breda – ADO den Haag : | | |
| 16:59 SC Heerenveen – Heracles Almelo : | | |
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| 17:00 Crystal Palace – Tottenham Hotspur : | | |
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| 17:59 Start IK – Haugesund : | | |
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| 17:59 Kryliya Sovetov – Tom Tomsk : | | |
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| 18:00 Nurnberg – Hertha Berlin : | | |
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| 18:59 FC Twente Enschede – FC Utrecht : | | |
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| 19:29 Lorient – Nantes : | | |
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| 19:29 Sporting Lisbon – FC Arouca : | | |
| 19:29 Belenenses – Rio Ave : | | |
| 19:29 Gil Vicente – Academica Coimbra : | | |
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| 19:30 Chelsea – Hull City : | | |
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| 20:00 Borussia Dortmund – Eintracht Braunschweig : | | |
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| 20:29 Honefoss BK – Sandnes Ulf : | | |
| 20:29 Sarpsborg 08 – Sogndal : | | |
| 20:29 Tromso – Aalesund FK : | | |
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| 20:29 FC Krasnodar – Dynamo Moscow : | | |
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| 21:14 Maritimo – Benfica : | | |
| 21:14 Vitoria Setubal – Porto : | | |
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| 21:29 Viking – Brann : | | |
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| 21:29 Akhisar Belediyespor – Elazigspor : | | |
| 21:29 Eskisehirspor – Bursaspor : | | |
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| 21:30 Barcelona – Levante : | | |
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| 22:29 Lazio – Juventus : | | |
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| 23:14 Besiktas – Trabzonspor : | | |
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| 23:29 Paris Saint Germain – Ajaccio : | | |
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| 23:30 Osasuna – Granada : | | |
| 23:30 Real Madrid – Real Betis : | | |
| 01:30 Sevilla – Atletico Madrid : | | |
