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| 03:30 Universidad Catolica Santiago – Union La Calera 1:2 | 1.48 | 4.20 | 6.25 | 1 | 2-1 | O |
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| 04:15 Club Atletico Gimnasia y Esgrima – Club Atletico Lanus 1:0 | 3.35 | 2.85 | 2.40 | X2 | 1-2 | U |
| 04:15 Club Atletico Tigre – Club Atletico Huracan 1:1 | 2.36 | 2.69 | 3.68 | X2 | 1-2 | U |
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| 14:00 Gimcheon Sangmu – Gangwon 0:3 | 3.06 | 3.15 | 2.36 | X2 | 1-2 | O |
| 14:00 Jeonbuk Hyundai Motors – Incheon United 1:2 | 1.89 | 3.42 | 4.08 | X2 | 1-2 | U |
| 14:00 Seoul – Bucheon 1995 3:0 | 1.65 | 3.62 | 5.42 | 1 | 2-1 | U |
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| 14:30 Shenzhen Peng City – Beijing Guoan 0:1 | 3.66 | 3.65 | 2.00 | 1X | 2-1 | O |
| 15:05 Chengdu Rongcheng – Yunnan Yukun 2:1 | 1.41 | 5.37 | 6.56 | 1 | 2-1 | O |
| 15:05 Wuhan Three Towns – Zhejiang Professional 2:0 | 3.24 | 3.58 | 2.18 | 2 | 1-2 | O |
| 15:30 Shanghai Port – Chongqing Tongliangloong 1:2 | 1.94 | 3.68 | 3.85 | X2 | 1-2 | O |
| 15:30 Tianjin Tiger – Shandong Taishan 1:2 | 4.46 | 3.56 | 1.84 | 2 | 1-2 | O |
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| 17:30 NK Lokomotiva – Slaven Belupo 2:1 | 2.21 | 3.22 | 3.22 | 1X | 1-0 | U |
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| 17:30 Horsens – Esbjerg fB 4:1 | 2.05 | 3.35 | 3.38 | 1X | 2-1 | O |
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| 18:00 Sochi – Krylia Sovetov 2:1 | 2.61 | 3.48 | 2.90 | 1X | 2-1 | U |
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| 18:30 Hvidovre – Kolding 2:1 | 2.09 | 3.30 | 3.32 | 1X | 1-0 | U |
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| 18:30 Dinamo Tbilisi – Gagra 0:1 | 1.59 | 3.52 | 5.29 | X2 | 0-1 | U |
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| 19:00 Haka – JaPS 5:0 | 1.62 | 3.64 | 4.82 | X2 | 1-2 | O |
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| 19:30 Hillerod – Lyngby 1:3 | 2.78 | 3.50 | 2.28 | X2 | 1-2 | U |
| 19:30 Horsens – Esbjerg fB 4:1 | 2.17 | 3.36 | 3.18 | 1X | 1-0 | U |
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| 19:45 Machida Zelvia – Shabab Al-Ahli Dubai 1:0 | 2.45 | 3.20 | 3.06 | X2 | 0-1 | U |
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| 20:00 Blau-Weiss Linz – Wolfsberger AC 3:0 | 2.02 | 3.44 | 3.54 | 1X | 2-1 | U |
| 20:00 Rheindorf Altach – WSG Tirol 0:0 | 2.21 | 3.12 | 3.38 | 1X | 1-0 | U |
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| 20:15 Hajduk Split – Osijek 0:1 | 1.37 | 4.45 | 8.40 | X2 | 2-2 | U |
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| 20:15 CSKA Moscow – Rostov 1:1 | 2.11 | 3.50 | 3.91 | 1 | 2-1 | O |
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| 20:30 Hvidovre – Kolding 2:1 | 1.95 | 3.22 | 4.00 | 1X | 1-0 | U |
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| 20:30 Torpedo Kutaisi – Samgurali Tskhaltubo 6:1 | 1.94 | 3.20 | 3.66 | 1 | 2-1 | U |
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| 20:30 Athletic Bilbao – Osasuna 1:0 | 1.89 | 3.60 | 4.78 | X2 | 1-2 | U |
| 20:30 Mallorca – Valencia 1:1 | 2.65 | 3.27 | 3.00 | 1X | 1-0 | U |
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| 20:30 Orebro – IFK Norrkoping 2:1 | 2.97 | 3.56 | 2.19 | 1X | 2-1 | O |
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| 21:30 Hillerod – Lyngby 1:3 | 3.49 | 3.32 | 2.06 | X2 | 0-1 | U |
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| 22:00 Ried – Grazer AK 2:1 | 2.21 | 3.15 | 3.36 | X2 | 0-1 | U |
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| 22:00 Genk – R. Charleroi 1:1 | 1.94 | 3.60 | 3.91 | 1 | 2-1 | U |
| 22:00 Oud-Heverlee Leuven – K.V.C. Westerlo 0:2 | 2.78 | 3.52 | 2.48 | X2 | 0-1 | U |
| 22:00 Standard Liege – Royal Antwerp 1:2 | 2.64 | 3.22 | 2.79 | 1X | 1-0 | U |
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| 22:15 Coventry City – Portsmouth 5:1 | 1.63 | 3.94 | 4.98 | 1 | 2-1 | O |
| 22:15 Leicester City – Hull City 2:2 | 2.05 | 3.56 | 3.34 | 1 | 2-1 | U |
| 22:15 Norwich City – Derby County 2:1 | 2.03 | 3.48 | 3.48 | 1X | 1-0 | U |
| 22:15 Oxford United – Wrexham 0:1 | 2.44 | 3.22 | 2.89 | 1X | 2-1 | O |
| 22:15 Queens Park Rangers – Swansea City 1:2 | 2.25 | 3.30 | 3.13 | 1X | 1-0 | U |
| 22:15 Southampton – Bristol City 2:2 | 1.42 | 4.60 | 6.84 | X2 | 1-2 | U |
| 22:15 Stoke City – Millwall 1:3 | 3.59 | 3.62 | 1.95 | 1X | 2-1 | O |
| 22:15 West Bromwich Albion – Watford 3:0 | 1.75 | 3.64 | 4.56 | 1 | 2-1 | O |
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| 22:15 Bradford City – Plymouth Argyle 1:1 | 2.68 | 3.34 | 2.50 | 1X | 2-1 | U |
| 22:15 Doncaster Rovers – Lincoln City 0:2 | 3.42 | 3.58 | 2.02 | X2 | 1-2 | U |
| 22:15 Rotherham United – Luton Town 0:2 | 4.30 | 3.94 | 1.72 | X2 | 1-2 | U |
| 22:15 Stevenage – Barnsley 1:0 | 1.78 | 3.55 | 4.46 | 1X | 2-1 | U |
| 22:15 Stockport County – Mansfield Town 0:1 | 1.57 | 4.30 | 5.06 | 1 | 2-1 | O |
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| 22:15 Cambridge United – Grimsby Town 1:2 | 1.81 | 3.64 | 4.08 | X2 | 1-2 | U |
| 22:15 Cheltenham Town – Tranmere Rovers 1:3 | 2.31 | 3.34 | 2.94 | 1X | 1-0 | U |
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| 22:15 Hartlepool United – Southend United 4:3 | 3.92 | 3.42 | 1.81 | 2 | 1-2 | O |
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| 22:15 Dunfermline Athletic – St. Johnstone 0:2 | 4.04 | 3.12 | 1.88 | 2 | 1-2 | U |
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| 22:30 Universitario de Vinto – ABB 5:2 | 1.63 | 3.75 | 4.56 | X2 | 1-2 | O |
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| 22:30 Brighton & Hove Albion – Chelsea 3:0 | 2.59 | 3.81 | 2.72 | 1X | 2-1 | O |
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| 23:00 Girona – Real Betis 2:3 | 2.51 | 3.40 | 3.09 | 1X | 2-1 | U |
| 23:00 Real Madrid – Deportivo Alaves 2:1 | 1.27 | 6.76 | 12.40 | X2 | 1-2 | O |
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| 01:30 Gualberto Villarroel – Club Aurora 1:1 | 1.83 | 3.76 | 3.48 | X2 | 1-2 | O |
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| 02:30 Brooklyn FC – Sacramento Republic 1:1 | 3.64 | 2.83 | 2.12 | X2 | 1-2 | U |
