|
| 04:00 Gremio Porto Alegrense – Clube Atletico Mineiro 2:1 | 2.21 | 3.41 | 3.37 | 1X | 2-1 | U | no |
| 04:00 Sociedade Esportiva Palmeiras – Fluminense 2:1 | 1.84 | 3.62 | 4.48 | 1 | 2-1 | U | no |
|
| 16:00 Geylang International – Young Lions 1:1 | 1.33 | 5.30 | 6.30 | 1 | 3-1 | O | yes |
|
| 19:15 Tractor Tabriz – Gol Gohar 1:0 | 1.51 | 3.38 | 6.57 | 1X | 2-0 | U | no |
|
| 21:00 Al Ittihad Kalba – Al Dhafra 1:1 | 2.09 | 3.38 | 3.08 | X2 | 1-2 | U | no |
| 21:00 Al Jazira Abu Dhabi – Al Sharjah 5:0 | 2.36 | 3.36 | 2.57 | X2 | 0-3 | U | no |
|
| 21:15 Samsunspor – Skendija 4:0 | 1.33 | 5.69 | 9.65 | 1 | 2-1 | O | no |
| 21:15 Rijeka – AC Omonia 3:1 | 2.26 | 3.38 | 3.40 | X2 | 1-2 | O | no |
| 21:15 Fiorentina – Jagiellonia Bialystok 0:3 | 1.55 | 4.37 | 6.30 | 1 | 2-1 | O | no |
| 21:15 Celje – KF Drita 3:2 | 1.34 | 5.62 | 9.30 | 1 | 2-1 | O | no |
|
| 21:15 Crvena Zvezda – Lille OSC 0:1 | 2.84 | 3.56 | 2.61 | 1X | 2-1 | U | no |
| 21:15 VfB Stuttgart – Celtic 0:1 | 1.41 | 5.58 | 7.75 | 1 | 3-1 | O | no |
| 21:15 Ferencvarosi – Ludogorets 1945 2:0 | 1.62 | 4.36 | 5.84 | 1 | 1-0 | U | no |
| 21:15 Viktoria Plzen – Panathinaikos 1:1 | 2.10 | 3.48 | 3.96 | 1X | 2-1 | U | no |
|
| 22:00 Al-Duhail – Al Sadd 1:3 | 3.20 | 3.88 | 1.89 | 2 | 1-2 | O | yes |
| 22:00 Al-Gharafa – Al Rayyan 3:2 | 3.57 | 4.20 | 1.72 | 1X | 2-1 | O | yes |
|
| 22:30 Al-Fateh Al-Ahsa – Damac 1:1 | 1.67 | 3.74 | 4.31 | 1 | 2-0 | U | no |
| 22:30 Al-Riyadh SC – Al-Ahli Jeddah 0:1 | 7.65 | 4.85 | 1.31 | 1X | 2-1 | O | no |
|
| 23:30 AZ Alkmaar – Noah Yerevan 4:0 | 1.30 | 5.85 | 11.20 | 1 | 2-1 | O | no |
| 23:30 Crystal Palace – Zrinjski 2:0 | 1.16 | 8.05 | 21.00 | 1 | 2-1 | O | no |
| 23:30 Lausanne-Sport – Sigma Olomouc 1:2 | 2.17 | 3.39 | 3.62 | 1X | 2-1 | U | no |
| 23:30 Lech Poznan – Kuopion Palloseura 1:0 | 1.22 | 7.25 | 13.60 | 1 | 2-1 | O | no |
|
| 23:30 Bologna 1909 – Brann 1:0 | 1.52 | 4.50 | 7.26 | 1 | 2-1 | O | no |
| 23:30 Celta – P.A.O.K. 1:0 | 1.72 | 3.94 | 5.53 | 1 | 2-1 | O | no |
| 23:30 Genk – Dinamo Zagreb 1:3 | 2.41 | 3.60 | 3.10 | 1X | 2-1 | U | no |
| 23:30 Nottingham Forest – Fenerbahce 1:2 | 1.61 | 4.46 | 5.83 | 1 | 2-0 | U | no |
|
| 23:45 Club Atletico Sarmiento Junin – Union de Santa Fe 1:3 | 3.40 | 2.88 | 2.35 | 2X | 0-2 | U | no |
| 23:45 Racing Club de Avellaneda – Independiente Rivadavia 1:1 | 1.83 | 3.20 | 4.82 | 2X | 0-2 | U | no |
|
| 01:00 Club Rubio Nu – Club Sportivo San Lorenzo 2:0 | 2.48 | 3.01 | 2.99 | 2X | 0-2 | U | no |
|
| 01:30 Santos – CR Vasco da Gama 2:1 | 1.92 | 3.60 | 4.10 | X2 | 1-2 | U | no |
|
| 02:00 Estudiantes de Rio Cuarto – Club Atletico Huracan 2:0 | 3.86 | 2.67 | 2.30 | 2X | 0-2 | U | no |
| 02:00 River Plate Buenos Aires – Club Atletico Banfield 3:1 | 1.49 | 3.88 | 7.21 | 1 | 2-1 | U | no |
|
| 02:30 Coritiba – Sao Paulo 0:1 | 3.02 | 3.17 | 2.53 | 2X | 0-2 | U | no |
|
| 03:00 Deportivo Recoleta – Club Nacional Asuncion 2:2 | 3.44 | 3.14 | 2.17 | 2X | 0-2 | U | no |
