|
| 19:00 Al-Okhdood – Al-Riyadh SC 2:2 | 2.40 | 3.04 | 2.74 | 1X | 2-0 | U | no |
| 21:00 Damac – Al Nassr 1:2 | 8.95 | 7.30 | 1.17 | 2 | 1-3 | O | yes |
| 21:00 Ettifaq Dammam – Neom SC 0:0 | 2.57 | 3.28 | 2.40 | X2 | 0-3 | U | no |
|
| 21:00 TS Galaxy – Marumo Gallants 2:0 | 2.10 | 2.74 | 3.87 | 2X | 0-2 | U | no |
|
| 21:15 AZ Alkmaar – Excelsior 1:1 | 1.35 | 5.58 | 8.10 | X2 | 1-2 | O | no |
|
| 21:15 Galatasaray – Atletico Madrid 1:1 | 3.40 | 3.92 | 2.15 | 1X | 2-1 | O | yes |
| 21:15 Qarabag – Eintracht Frankfurt 3:2 | 3.23 | 3.90 | 2.22 | 1X | 2-1 | O | yes |
|
| 21:30 Ceramica Cleopatra – Al Ittihad Alexandria 3:1 | 1.95 | 2.90 | 4.14 | 1X | 2-0 | U | no |
| 21:30 Smouha – Pharco 2:0 | 1.83 | 2.78 | 5.17 | 1X | 2-0 | U | no |
|
| 21:30 UD Leiria – Vizela 2:2 | 2.64 | 3.04 | 2.70 | 2X | 0-2 | U | no |
|
| 23:15 Southampton – Sheffield United 1:0 | 2.28 | 3.60 | 2.85 | X2 | 1-2 | U | no |
| 23:15 Watford – Portsmouth 1:1 | 1.72 | 3.60 | 4.80 | 1 | 2-1 | O | no |
|
| 23:15 Carlisle United – York City 0:3 | 3.04 | 3.32 | 2.13 | 1X | 2-1 | U | no |
| 23:15 Forest Green Rovers – Altrincham 1:1 | 1.35 | 4.45 | 7.48 | 1 | 2-1 | O | no |
| 23:15 Halifax Town – Morecambe 1:0 | 2.11 | 3.42 | 3.00 | 1X | 2-1 | U | yes |
| 23:15 Solihull Moors – Rochdale 0:1 | 3.48 | 3.56 | 1.88 | 2 | 0-3 | U | yes |
| 23:15 Wealdstone – Tamworth PP | 2.18 | 3.32 | 2.95 | 1X | 2-1 | U | no |
|
| 23:30 Stoke City – Middlesbrough 1:2 | 2.94 | 3.30 | 2.36 | 1X | 1-0 | U | no |
|
| 23:30 Atalanta – Athletic Bilbao 2:3 | 1.83 | 3.82 | 4.82 | 1 | 2-1 | U | no |
| 23:30 Bayern Munich – Royale Union Saint-Gilloise 2:0 | 1.13 | 11.00 | 23.00 | 1 | 4-0 | O | no |
| 23:30 Chelsea – Pafos 1:0 | 1.16 | 9.20 | 23.00 | 1 | 2-1 | O | no |
| 23:30 Juventus – Benfica 2:0 | 1.80 | 3.80 | 5.08 | 1 | 2-1 | O | no |
| 23:30 Newcastle United – PSV Eindhoven 3:0 | 1.41 | 5.79 | 7.42 | 1 | 3-1 | O | no |
| 23:30 Olympique de Marseille – Liverpool 0:3 | 3.92 | 3.98 | 1.96 | 2 | 1-2 | O | yes |
| 23:30 Slavia Prague – Barcelona 2:4 | 8.10 | 6.10 | 1.37 | 2 | 1-3 | O | yes |
