|
| 03:30 Emelec – Club Social y Deportivo Macara 0:2 | 2.25 | 3.20 | 3.20 | 2X | 0-2 | U | no |
|
| 13:30 Machida Zelvia – Ulsan Hyundai 3:1 | 1.55 | 4.20 | 6.14 | 1 | 2-1 | O | yes |
| 13:30 Vissel Kobe – Chengdu Rongcheng 2:2 | 1.60 | 3.93 | 5.99 | 1 | 2-1 | O | no |
| 15:45 Buriram United – Gangwon 2:2 | 2.12 | 3.43 | 3.52 | 1X | 2-1 | O | yes |
| 15:45 Darul Takzim – Shanghai Port 0:0 | 1.39 | 5.17 | 7.37 | 1 | 2-1 | O | no |
|
| 16:15 Shams Azar Qazvin – Gol Gohar 1:1 | 3.57 | 2.56 | 2.33 | 1X | 2-0 | U | no |
| 16:15 Zob Ahan – Tractor Tabriz 0:0 | 4.66 | 2.88 | 1.86 | 2X | 0-2 | U | no |
| 17:15 Paykan – Persepolis 0:1 | 4.80 | 3.14 | 1.75 | 2X | 0-2 | U | no |
| 18:30 Esteghlal Khuzestan – Kheybar Khorramabad 0:1 | 3.16 | 2.60 | 2.51 | 2X | 0-2 | U | no |
|
| 19:00 Kairat – Olympiacos Piraeus 0:1 | 6.96 | 4.62 | 1.52 | 1X | 3-0 | U | no |
| 21:15 Bayern Munich – Sporting Clube de Portugal 3:1 | 1.29 | 6.55 | 11.40 | 1 | 3-1 | O | no |
|
| 23:15 Blackburn Rovers – Oxford United 1:1 | 1.75 | 3.52 | 4.76 | 1 | 2-0 | U | no |
| 23:15 Charlton Athletic – Middlesbrough 1:2 | 3.38 | 3.24 | 2.16 | 1X | 2-1 | U | no |
| 23:15 Preston North End – Coventry City 1:1 | 3.71 | 3.54 | 1.94 | 2 | 0-3 | U | yes |
| 23:15 Sheffield United – Norwich City 1:1 | 1.64 | 3.90 | 4.98 | 1 | 2-0 | U | no |
| 23:15 Southampton – West Bromwich Albion 3:2 | 1.83 | 3.70 | 3.98 | 1X | 2-1 | U | no |
| 23:15 Swansea City – Portsmouth 1:0 | 2.18 | 3.28 | 3.28 | X2 | 1-2 | U | no |
| 23:15 Watford – Sheffield Wednesday 1:1 | 1.51 | 4.20 | 5.96 | 1 | 2-1 | U | no |
|
| 23:15 Doncaster Rovers – Stockport County 0:2 | 2.46 | 3.28 | 2.77 | 1X | 2-1 | U | no |
| 23:15 Exeter City – Wimbledon 1:0 | 2.31 | 3.25 | 3.06 | 1X | 2-1 | U | no |
| 23:15 Leyton Orient – Luton Town 1:1 | 2.94 | 3.22 | 2.40 | 1X | 2-1 | U | no |
| 23:15 Lincoln City – Barnsley 3:1 | 2.18 | 3.42 | 3.16 | 1X | 2-1 | U | no |
| 23:15 Mansfield Town – Bolton Wanderers 0:1 | 4.22 | 3.58 | 1.82 | 1X | 3-0 | U | yes |
| 23:15 Northampton Town – Huddersfield Town 1:1 | 3.20 | 3.24 | 2.24 | 1X | 2-1 | U | no |
| 23:15 Port Vale – Bradford City PP | 2.67 | 3.25 | 2.56 | 1X | 2-1 | U | yes |
| 23:15 Stevenage – Cardiff City 0:1 | 2.76 | 3.16 | 2.54 | 2X | 0-2 | U | no |
| 23:15 Wycombe Wanderers – Plymouth Argyle 0:1 | 1.67 | 3.74 | 4.98 | X2 | 1-2 | U | no |
|
| 23:15 Barnet – Bristol Rovers 4:0 | 1.59 | 3.80 | 5.53 | X2 | 1-2 | O | no |
| 23:15 Barrow – Tranmere Rovers 0:3 | 2.66 | 3.22 | 2.55 | 1X | 2-1 | U | no |
| 23:15 Bromley – Crawley Town 3:1 | 1.81 | 3.68 | 4.04 | X2 | 1-2 | U | no |
| 23:15 Cambridge United – Chesterfield 1:1 | 2.06 | 3.12 | 3.73 | 1X | 2-0 | U | no |
| 23:15 Fleetwood Town – Salford City 1:1 | 2.74 | 3.44 | 2.36 | 1X | 2-1 | U | no |
| 23:15 Harrogate Town – Accrington Stanley 0:2 | 3.20 | 3.30 | 2.19 | 1X | 2-1 | U | no |
| 23:15 Notts County – Milton Keynes Dons 3:2 | 2.60 | 3.16 | 2.64 | 1X | 2-1 | U | no |
| 23:15 Shrewsbury Town – Grimsby Town 1:1 | 3.16 | 3.32 | 2.20 | 2X | 1-2 | U | no |
| 23:15 Swindon Town – Cheltenham Town 0:1 | 1.42 | 4.45 | 6.93 | X2 | 1-2 | U | no |
|
| 23:15 Briton Ferry – The New Saints 0:2 | 12.50 | 7.40 | 1.12 | 2 | 1-2 | O | no |
| 23:15 Pen-y-Bont – Barry Town 1:1 | 1.77 | 3.66 | 3.82 | 1 | 2-1 | U | yes |
|
| 23:30 Queens Park Rangers – Birmingham City 2:1 | 2.85 | 3.30 | 2.42 | 1X | 2-1 | U | no |
|
| 23:30 Reading – Peterborough United 1:2 | 2.21 | 3.35 | 3.16 | X2 | 1-2 | U | no |
|
| 23:30 AS Monaco – Galatasaray 1:0 | 2.12 | 3.94 | 3.44 | 1X | 3-0 | O | yes |
| 23:30 Atalanta – Chelsea 2:1 | 3.38 | 3.68 | 2.24 | 2X | 1-2 | O | yes |
| 23:30 Barcelona – Eintracht Frankfurt 2:1 | 1.19 | 8.90 | 15.00 | 1 | 4-0 | O | no |
| 23:30 Internazionale Milano – Liverpool 0:1 | 2.03 | 3.82 | 3.81 | 1X | 3-0 | U | no |
| 23:30 PSV Eindhoven – Atletico Madrid 2:3 | 3.06 | 3.94 | 2.30 | 2X | 1-2 | O | yes |
| 23:30 Royale Union Saint-Gilloise – Olympique de Marseille 2:3 | 3.09 | 3.60 | 2.42 | X2 | 0-3 | O | no |
| 23:30 Tottenham Hotspur – Slavia Prague 3:0 | 1.45 | 4.98 | 7.90 | 1 | 2-1 | U | no |
|
| 02:30 Jorge Wilstermann – Gualberto Villarroel 2:2 | 2.19 | 3.56 | 2.76 | 1X | 2-1 | O | yes |
