|
| 03:30 Manta – SD Aucas 1:1 | 3.31 | 3.30 | 2.15 | 2X | 0-1 | U | no |
|
| 11:15 Melbourne City – Sanfrecce Hiroshima 0:2 | 4.06 | 3.50 | 1.93 | 2 | 1-2 | O | yes |
| 13:30 Gangwon – Shanghai Shenhua 2:1 | 1.58 | 4.30 | 5.35 | 1X | 1-0 | U | no |
| 13:30 Machida Zelvia – Seoul 1:1 | 1.70 | 3.90 | 4.80 | 1 | 2-0 | U | no |
| 15:45 Buriram United – Darul Takzim 2:1 | 2.66 | 3.46 | 2.56 | 1X | 2-1 | O | no |
| 19:30 Shabab Al-Ahli Dubai – Tractor Tabriz 1:1 | 1.87 | 3.48 | 4.34 | 1 | 2-0 | U | no |
|
| 20:15 Athletic Bilbao – Arsenal 0:2 | 4.82 | 3.60 | 1.88 | X2 | 1-2 | U | yes |
| 20:15 PSV Eindhoven – Royale Union Saint-Gilloise 1:3 | 1.97 | 3.92 | 3.98 | 1 | 2-1 | O | no |
|
| 20:30 Boulogne – Bastia 1:0 | 3.26 | 3.22 | 2.30 | 1X | 2-1 | U | no |
|
| 20:30 Helsingborgs – Landskrona BoIS 0:0 | 2.26 | 3.44 | 3.06 | 1X | 1-0 | U | no |
|
| 21:00 Chippa United – ORBIT College 2:1 | 2.11 | 2.80 | 3.98 | 1X | 2-0 | U | no |
| 21:00 Durban City – Siwelele 2:0 | 2.38 | 2.79 | 3.29 | 2X | 0-2 | U | no |
| 21:00 Kaizer Chiefs – Sekhukhune United 1:3 | 2.14 | 2.67 | 4.15 | 2X | 0-2 | U | no |
|
| 21:30 MVV Maastricht – Den Bosch 2:4 | 2.62 | 3.62 | 2.46 | 1X | 2-1 | O | no |
| 21:30 Helmond Sport – Utrecht II 2:1 | 1.66 | 4.05 | 4.72 | 1 | 2-1 | O | no |
| 21:30 Oss – VVV-Venlo 2:1 | 2.62 | 3.64 | 2.45 | 1X | 2-1 | U | no |
| 21:30 Waalwijk – Vitesse 1:1 | 1.26 | 6.05 | 9.75 | 1 | 3-1 | O | no |
|
| 21:45 Al-Hilal Riyadh – Al-Duhail 2:1 | 1.26 | 6.15 | 10.50 | 1 | 3-1 | O | no |
|
| 22:30 San Antonio Bulo Bulo – Oriente Petrolero 1:1 | 1.70 | 4.05 | 4.06 | 1 | 3-1 | O | yes |
|
| 22:30 Benfica – Qarabag 2:3 | 1.24 | 6.92 | 15.00 | 1 | 2-1 | O | no |
| 22:30 Juventus – Borussia Dortmund 4:4 | 2.04 | 3.69 | 3.94 | 1X | 1-0 | U | no |
| 22:30 Real Madrid – Olympique de Marseille 2:1 | 1.43 | 5.42 | 7.47 | 1 | 3-1 | O | no |
| 22:30 Tottenham Hotspur – Villarreal 1:0 | 1.93 | 4.04 | 4.02 | 1 | 2-1 | O | no |
|
| 01:00 Real Tomayapo – Guabira PP | 2.25 | 3.38 | 2.92 | 2X | 0-1 | U | no |
|
| 03:00 Inter Miami – Seattle Sounders 3:1 | 1.96 | 4.05 | 3.52 | 1 | 2-1 | O | no |
