|
| 17:30 Astana – Lausanne-Sport 0:2 | 2.71 | 3.73 | 2.46 | X2 | 0-2 | O | no |
|
| 18:30 ZED – Ceramica Cleopatra 0:0 | 3.49 | 3.08 | 2.12 | 1X | 2-1 | U | no |
|
| 18:30 Kuopion Palloseura – Rigas Futbola skola 1:0 | 2.29 | 3.64 | 3.07 | X2 | 1-1 | U | no |
|
| 19:00 Al Rayyan – Al-Sailiya 3:1 | 1.31 | 5.25 | 7.75 | 1 | 2-1 | O | no |
|
| 19:30 Ararat - Armenia – AC Sparta Prague 1:2 | 5.75 | 5.04 | 1.50 | 1X | 2-1 | U | no |
| 19:30 Sabah Baku – Levski Sofia 0:2 | 2.55 | 3.22 | 2.94 | 1X | 2-1 | U | no |
|
| 19:30 Midtjylland – Fredrikstad 2:0 | 1.40 | 5.08 | 7.80 | 1 | 2-1 | O | no |
|
| 20:30 AC Omonia – Araz-Naxcıvan 5:0 | 1.38 | 4.75 | 9.40 | 1 | 1-0 | U | no |
| 20:30 Gyori ETO – AIK 2:0 | 2.71 | 3.27 | 2.71 | X2 | 0-2 | U | no |
| 20:30 Hammarby – Rosenborg 0:1 | 2.21 | 3.31 | 3.45 | X2 | 1-1 | U | no |
| 20:30 Sheriff Tiraspol – Anderlecht 1:1 | 3.45 | 3.66 | 2.08 | 1X | 2-1 | U | no |
|
| 20:30 Brann – Hacken 0:1 | 1.61 | 4.53 | 5.14 | 1 | 2-1 | O | no |
| 20:30 Noah Yerevan – Lincoln Red Imps 0:0 | 1.31 | 5.44 | 10.90 | 1 | 2-1 | O | no |
| 20:30 Wolfsberger AC – P.A.O.K. 0:0 | 3.10 | 3.37 | 2.39 | 2X | 0-2 | U | no |
|
| 21:00 Al Shamal – Al Ahli Doha 2:0 | 2.47 | 3.60 | 2.46 | X2 | 1-2 | O | no |
|
| 21:00 Arda Kardzhali – Zalgiris Kaunas 2:0 | 2.09 | 3.31 | 3.80 | X2 | 1-1 | U | no |
| 21:00 Beitar Jerusalem – Riga FC 3:1 | 2.13 | 3.68 | 3.31 | X2 | 1-1 | U | no |
| 21:00 Brondby – Vikingur Reykjavik 4:0 | 1.33 | 5.31 | 9.90 | 1 | 2-1 | O | no |
| 21:00 Vaduz – AZ Alkmaar 0:1 | 10.20 | 6.55 | 1.26 | 2 | 1-4 | O | no |
|
| 21:00 Breidablik UBK – Zrinjski 1:2 | 2.30 | 3.41 | 3.24 | X2 | 1-1 | U | no |
|
| 21:30 Pyramids – Ismaily 1:0 | 1.36 | 4.40 | 8.30 | 1 | 1-0 | U | no |
|
| 21:30 AEK Athens – Aris Limassol 1:1 | 1.60 | 3.98 | 6.08 | 1 | 1-0 | U | no |
| 21:30 Besiktas – St Patricks Athletic 3:2 | 1.12 | 9.30 | 24.00 | 1 | 3-1 | O | no |
| 21:30 Maccabi Haifa – Rakow Czestochowa 0:2 | 2.94 | 3.25 | 2.53 | X2 | 1-2 | U | no |
| 21:30 Neman Grodno – KI Klaksvik 2:0 | 2.05 | 3.59 | 3.61 | X2 | 1-1 | U | no |
|
| 21:30 Shakhtar Donetsk – Panathinaikos 0:0 | 1.74 | 3.90 | 4.93 | 1 | 1-0 | U | no |
| 21:30 Utrecht – Servette 2:1 | 1.56 | 4.74 | 5.45 | 1 | 2-1 | O | no |
| 21:30 KF Drita – FCSB 1:3 | 3.66 | 3.61 | 2.05 | 1X | 2-1 | U | no |
| 21:30 Maccabi Tel Aviv – Hamrun Spartans 3:1 | 1.24 | 6.71 | 11.90 | 1 | 2-1 | O | no |
|
| 21:45 Jagiellonia Bialystok – Silkeborg 2:2 | 2.25 | 3.39 | 3.29 | X2 | 1-1 | U | no |
| 22:00 Spartak Trnava – CS Universitatea Craiova 4:1 | 2.39 | 3.22 | 3.19 | X2 | 1-2 | U | no |
|
| 22:00 Braga – CFR Cluj 2:0 | 1.43 | 4.58 | 8.55 | 1 | 1-0 | U | no |
|
| 22:15 Dinamo City – Hajduk Split 1:0 | 3.32 | 3.76 | 2.10 | 1X | 2-1 | U | no |
| 22:15 Dundee United – Rapid Wien 2:2 | 3.33 | 3.65 | 2.13 | 1X | 2-1 | U | no |
| 22:30 Austria Wien – Banik Ostrava 1:1 | 1.74 | 4.00 | 4.64 | 1 | 1-0 | U | no |
| 22:30 Santa Clara – Larne 0:0 | 1.15 | 7.85 | 23.00 | 1 | 3-0 | U | no |
|
| 22:30 Legia Warsaw – AEK Larnaca 2:1 | 1.69 | 4.38 | 4.63 | 1 | 1-0 | U | no |
