|
| 03:45 Argentinos Juniors – Estudiantes de Rio Cuarto : | 1.42 | 4.12 | 9.55 | 1X | 1-0 | U |
| 03:45 Rosario Central – Racing Club de Avellaneda : | 2.30 | 3.00 | 3.50 | X2 | 0-1 | U |
|
| 18:00 Dukagjini – Lugano : | 5.29 | 3.74 | 1.62 | 2 | 1-2 | O |
|
| 18:30 Kairat – AC Omonia : | 2.22 | 3.32 | 3.20 | X2 | 0-1 | U |
|
| 19:00 Mikkelin Palloilijat – KaPa : | 2.03 | 3.42 | 3.18 | 1X | 1-0 | U |
|
| 19:30 Zalgiris Kaunas – KI Klaksvik : | 1.72 | 3.60 | 4.84 | X2 | 1-2 | O |
| 20:30 Lech Poznan – AGF Aarhus : | 1.76 | 3.70 | 4.42 | 1 | 2-1 | O |
|
| 20:30 Copenhagen – Polissya Zhytomyr : | 1.39 | 4.60 | 7.33 | 1 | 2-1 | O |
|
| 21:00 Barracas Central – CA Aldosivi : | 2.35 | 2.82 | 3.66 | 1X | 2-1 | U |
|
| 21:00 CS Universitatea Craiova – Levski Sofia : | 1.86 | 3.47 | 4.18 | X2 | 1-2 | U |
| 21:00 Hapoel Be'er Sheva – Vikingur Reykjavik : | 1.57 | 4.08 | 5.48 | X2 | 1-2 | U |
| 21:30 Gornik Zabrze – Fenerbahce : | 6.60 | 4.28 | 1.47 | 2 | 1-2 | U |
| 21:30 Crvena Zvezda – Larne : | 1.06 | 13.20 | 22.00 | 1 | 4-1 | O |
| 21:45 Slovan Bratislava – Iberia 1999 : | 1.34 | 4.99 | 8.45 | 1 | 2-1 | O |
|
| 22:00 Rapid Wien – Santa Coloma : | 1.14 | 6.95 | 17.00 | 1 | 2-1 | O |
|
| 23:30 Defensa y Justicia – Deportivo Riestra : | 2.22 | 2.92 | 3.85 | X2 | 1-2 | U |
|
| 23:30 Botafogo de Futebol e Regatas – Gremio Porto Alegrense : | 1.74 | 3.64 | 5.19 | 1 | 2-1 | O |
| 23:30 Chapecoense – CR Vasco da Gama : | 3.17 | 3.17 | 2.43 | X2 | 0-1 | U |
| 23:30 Clube Atletico Mineiro – Red Bull Bragantino : | 2.20 | 3.35 | 3.46 | 1X | 1-0 | U |
| 23:30 Sao Paulo – Santos : | 2.04 | 3.47 | 3.78 | 1X | 1-0 | U |
|
| 01:45 Gimnasia y Esgrima La Plata – River Plate Buenos Aires : | 3.95 | 3.10 | 2.10 | 1X | 2-1 | U |
|
| 02:00 Mirassol – Clube do Remo : | 1.76 | 3.66 | 4.99 | 1 | 2-1 | U |
| 02:00 Sport Club Internacional – Flamengo : | 3.58 | 3.44 | 2.12 | X2 | 1-2 | U |
|
| 02:30 Pittsburgh Riverhounds – Tulsa : | 2.05 | 3.15 | 3.40 | X2 | 0-1 | U |
| 03:00 Louisville City – Birmingham Legion : | 1.34 | 4.90 | 6.68 | 1 | 2-1 | O |
