|
| 04:00 Corinthians Paulista – Coritiba 0:2 | 1.60 | 3.91 | 6.27 | 1 | 2-1 | O | no |
| 04:00 Flamengo – Cruzeiro Esporte Clube 2:0 | 1.60 | 3.97 | 6.12 | 1 | 2-1 | U | no |
|
| 04:30 Atletico Tucuman – CA Aldosivi 1:1 | 1.92 | 3.06 | 4.54 | 1X | 2-0 | U | no |
| 04:30 Independiente Rivadavia – Barracas Central 1:2 | 1.49 | 3.80 | 7.50 | 2X | 0-2 | U | no |
|
| 14:00 Igdir Alagoz Holding – Bodrum Belediyesi Bodrumspor 2:3 | 1.85 | 3.48 | 3.66 | 1 | 2-0 | U | no |
| 16:30 Boluspor – Arca Corum 1:2 | 3.51 | 3.68 | 1.84 | 2 | 1-2 | O | no |
|
| 18:30 Samgurali Tskhaltubo – Dinamo Batumi 1:1 | 1.80 | 3.38 | 4.00 | 1 | 2-1 | O | no |
| 19:30 Dila Gori – Meshakhte Tkibuli 0:1 | 1.70 | 3.50 | 4.38 | 1 | 2-1 | O | yes |
|
| 20:30 Esenler Erokspor – Bandırmaspor 1:1 | 1.36 | 4.30 | 7.60 | 1 | 2-1 | U | no |
|
| 21:00 Al Ain – Al Wasl 2:0 | 1.79 | 3.55 | 3.86 | 1 | 2-0 | U | no |
| 21:00 Baniyas – Al-Wahda Abu Dhabi 1:0 | 4.01 | 3.54 | 1.76 | 2 | 1-2 | O | yes |
|
| 21:15 AZ Alkmaar – AC Sparta Prague 2:1 | 1.78 | 3.81 | 4.40 | X2 | 1-2 | U | no |
| 21:15 Lech Poznan – Shakhtar Donetsk 1:3 | 2.63 | 3.41 | 2.80 | 1X | 2-1 | U | no |
| 21:15 Rijeka – Strasbourg 1:2 | 4.82 | 3.76 | 1.72 | 2 | 1-2 | O | yes |
| 21:15 Samsunspor – Rayo Vallecano 1:3 | 3.97 | 3.22 | 2.13 | 1X | 2-1 | U | no |
|
| 22:00 Al-Wakrah – Al Shamal 0:1 | 2.21 | 3.48 | 2.78 | 2 | 1-2 | O | yes |
| 22:00 Al-Sailiya – Al-Duhail 0:4 | 5.26 | 3.85 | 1.54 | 2 | 0-3 | U | yes |
| 22:00 Qatar SC – Al-Gharafa 2:0 | 2.51 | 3.44 | 2.38 | 2 | 1-2 | O | yes |
|
| 22:30 Al-Najma Unaizah – Damac 1:3 | 2.77 | 3.30 | 2.30 | 1X | 2-1 | U | no |
| 22:30 Al Hazm Rass – Al Kholood 2:1 | 2.81 | 3.30 | 2.27 | X2 | 0-3 | U | no |
| 22:30 Neom SC – Al-Taawon 2:2 | 2.30 | 3.30 | 2.77 | 1X | 2-1 | U | no |
|
| 23:30 Defensa y Justicia – Central Cordoba de Santiago 1:1 | 1.92 | 3.08 | 4.53 | 1X | 2-0 | U | no |
| 23:30 Deportivo Riestra – Club Atletico Gimnasia y Esgrima 0:0 | 1.89 | 2.86 | 5.32 | 2X | 0-2 | U | no |
|
| 23:30 Celje – AEK Athens 0:4 | 5.25 | 4.08 | 1.68 | 1X | 2-1 | U | yes |
| 23:30 Crystal Palace – AEK Larnaca 0:0 | 1.26 | 5.90 | 14.60 | 1 | 2-1 | O | no |
| 23:30 Fiorentina – Rakow Czestochowa 2:1 | 1.98 | 3.48 | 4.21 | 1 | 2-1 | O | yes |
| 23:30 Sigma Olomouc – 1. FSV Mainz 05 0:0 | 5.51 | 3.74 | 1.72 | 2 | 0-3 | U | yes |
|
| 23:30 Bologna 1909 – Roma 1:1 | 3.22 | 3.09 | 2.62 | 1X | 2-0 | U | no |
| 23:30 Celta – Lyon 1:1 | 2.05 | 3.52 | 4.10 | X2 | 1-2 | U | no |
| 23:30 Ferencvarosi – Braga 2:0 | 3.33 | 3.37 | 2.39 | X2 | 1-2 | U | no |
| 23:30 Genk – Freiburg 1:0 | 2.73 | 3.27 | 2.91 | X2 | 0-3 | U | no |
| 23:30 Lille OSC – Aston Villa 0:1 | 3.39 | 3.29 | 2.31 | X2 | 1-2 | U | no |
| 23:30 Nottingham Forest – Midtjylland 0:1 | 1.56 | 4.58 | 6.50 | 1 | 2-1 | U | no |
| 23:30 Panathinaikos – Real Betis 1:0 | 3.66 | 3.50 | 2.19 | 1X | 2-0 | U | no |
| 23:30 VfB Stuttgart – Porto 1:2 | 1.92 | 3.64 | 4.25 | 1X | 2-1 | U | no |
|
| 01:30 Clube do Remo – Fluminense 0:2 | 4.03 | 3.72 | 1.90 | 2X | 0-2 | U | yes |
|
| 01:45 Estudiantes de Rio Cuarto – Belgrano 0:1 | 3.42 | 2.80 | 2.40 | 1X | 2-0 | U | no |
| 01:45 Talleres de Cordoba – Instituto Atletico Central Cordoba 2:0 | 2.32 | 2.88 | 3.45 | 1X | 2-0 | U | no |
|
| 02:00 CR Vasco da Gama – Sociedade Esportiva Palmeiras 2:1 | 3.02 | 3.30 | 2.45 | X2 | 1-2 | U | no |
| 02:30 Sao Paulo – Chapecoense 2:0 | 1.41 | 4.78 | 8.10 | 1 | 2-1 | U | no |
