|
| 04:00 Libertad Loja – Manta 1:0 | 1.74 | 3.58 | 4.62 | 1 | 1-0 | U | yes |
|
| 21:00 Admira Wacker – Austria Wien II 2:1 | 1.49 | 4.20 | 6.09 | 1 | 1-0 | U | no |
|
| 21:00 AmaZulu – Mamelodi Sundowns 0:1 | 5.75 | 3.28 | 1.61 | 2X | 0-2 | U | no |
| 21:00 Kaizer Chiefs – Stellenbosch 1:2 | 1.64 | 3.20 | 5.70 | 2X | 0-2 | U | no |
|
| 21:15 Atletico Madrid – Club Brugge 4:1 | 1.40 | 5.58 | 8.05 | 1 | 2-1 | O | no |
|
| 22:30 Willem II – ADO Den Haag 0:1 | 3.46 | 3.75 | 1.93 | 2 | 1-2 | O | no |
| 22:30 Cambuur – Eindhoven 2:1 | 1.39 | 5.00 | 6.47 | 1 | 2-1 | O | no |
|
| 22:30 Al Hazm Rass – Al-Ittihad Jeddah 1:1 | 5.95 | 4.40 | 1.42 | 1X | 2-1 | O | yes |
| 22:30 Al-Khaleej – Al Kholood 2:3 | 2.01 | 3.34 | 3.30 | 1 | 2-1 | O | no |
| 22:30 Al-Taawon – Al-Hilal Riyadh 1:1 | 7.09 | 5.45 | 1.29 | 1X | 2-1 | O | no |
|
| 23:00 Ceramica Cleopatra – Ismaily 1:1 | 1.43 | 3.70 | 7.70 | 1X | 2-0 | U | no |
| 23:00 Ghazl El Mahalla – Pyramids 1:3 | 7.70 | 3.84 | 1.41 | 2X | 0-2 | U | no |
| 23:00 Haras El Hodoud – ENPPI 1:0 | 3.90 | 2.76 | 2.08 | 2X | 0-2 | U | no |
| 23:00 ZED – Zamalek 1:2 | 3.68 | 2.68 | 2.20 | 2X | 0-2 | U | no |
|
| 23:15 Blackburn Rovers – Bristol City 1:2 | 2.44 | 3.16 | 2.93 | 1X | 2-1 | U | no |
| 23:15 Hull City – Derby County 4:2 | 2.46 | 3.22 | 2.86 | 1X | 2-1 | U | no |
| 23:15 Middlesbrough – Leicester City 1:1 | 1.53 | 4.25 | 5.62 | X2 | 0-1 | O | no |
| 23:15 Swansea City – Preston North End 1:1 | 1.78 | 3.64 | 4.32 | 1 | 2-1 | U | no |
| 23:15 West Bromwich Albion – Charlton Athletic 1:1 | 2.00 | 3.22 | 3.90 | 1 | 2-1 | U | no |
| 23:15 Wrexham – Portsmouth 2:1 | 2.07 | 3.30 | 3.55 | 1X | 2-1 | U | no |
| 23:15 Watford – Ipswich Town 0:2 | 3.22 | 3.25 | 2.22 | 1X | 2-1 | U | no |
|
| 23:15 Northampton Town – Port Vale 0:1 | 2.37 | 3.08 | 3.11 | 1X | 2-0 | U | no |
| 23:15 Burton Albion – Stockport County 3:0 | 3.24 | 3.40 | 2.15 | 2 | 0-3 | U | no |
| 23:15 Doncaster Rovers – Luton Town PP | 2.50 | 3.35 | 2.60 | 1X | 2-0 | U | no |
| 23:15 Bradford City – Rotherham United 1:0 | 1.68 | 3.52 | 5.33 | 1X | 2-0 | U | no |
|
| 23:15 Accrington Stanley – Barnet 0:1 | 3.49 | 3.38 | 2.04 | 2X | 0-2 | U | no |
| 23:15 Salford City – Shrewsbury Town 1:2 | 1.66 | 3.74 | 4.91 | 1 | 2-1 | U | no |
|
| 23:15 Forest Green Rovers – Boston United 2:3 | 1.53 | 4.10 | 4.96 | 1 | 2-1 | O | no |
| 23:15 Halifax Town – Rochdale 2:2 | 4.73 | 3.54 | 1.65 | 1X | 3-0 | U | yes |
| 23:15 Scunthorpe United – York City 0:3 | 3.58 | 3.74 | 1.81 | 1X | 2-1 | O | yes |
| 23:15 Southend United – Boreham Wood 0:2 | 2.00 | 3.46 | 3.22 | 1X | 2-1 | U | no |
| 23:15 Tamworth – Altrincham 5:1 | 2.24 | 3.30 | 2.86 | 1X | 2-1 | U | no |
| 23:15 Wealdstone – Brackley Town 2:1 | 2.07 | 3.20 | 3.28 | X2 | 1-2 | U | no |
|
| 23:15 Queens Park – St. Johnstone 1:1 | 6.79 | 4.50 | 1.37 | 2 | 0-3 | U | no |
| 23:15 Dunfermline Athletic – Partick Thistle 2:2 | 3.05 | 2.99 | 2.29 | 2X | 0-2 | U | no |
|
| 23:15 Stirling Albion – Annan Athletic 2:0 | 3.16 | 3.38 | 2.05 | 2X | 0-2 | U | no |
| 23:15 Dumbarton – Clyde 0:0 | 3.18 | 3.44 | 2.02 | 1X | 2-1 | U | no |
| 23:15 Elgin City – Edinburgh FC 3:0 | 1.66 | 3.74 | 4.36 | 1 | 2-1 | O | yes |
|
| 23:15 Dundee United – Aberdeen 0:0 | 2.14 | 3.34 | 3.34 | X2 | 0-3 | O | no |
|
| 23:30 Platense – Defensa y Justicia 0:0 | 2.10 | 2.88 | 4.10 | 2X | 0-2 | U | no |
|
| 23:30 Southampton – Queens Park Rangers 5:0 | 1.68 | 3.88 | 4.65 | 1 | 2-1 | U | no |
|
| 23:30 Bayer 04 Leverkusen – Olympiacos Piraeus 0:0 | 1.88 | 4.08 | 4.20 | 1 | 2-1 | O | no |
| 23:30 Internazionale Milano – Bodo-Glimt 1:2 | 1.29 | 7.40 | 9.60 | 1 | 3-1 | O | no |
| 23:30 Newcastle United – Qarabag 3:2 | 1.18 | 11.00 | 13.40 | 1 | 3-1 | O | no |
|
| 00:30 San Lorenzo de Almagro – Instituto Atletico Central Cordoba 1:1 | 2.33 | 2.82 | 3.53 | 2X | 0-2 | U | no |
| 02:15 Central Cordoba de Santiago – Talleres de Cordoba 2:0 | 3.48 | 2.71 | 2.46 | 2X | 0-2 | U | no |
