|
| 18:30 NK Istra 1961 – Rijeka 1:2 | 3.37 | 2.92 | 2.30 | 1X | 2-1 | U | no |
|
| 18:35 Al Shabab Riyadh – Al-Najma Unaizah 0:0 | 1.40 | 4.33 | 6.48 | 1 | 1-0 | U | no |
|
| 19:00 Kairat – Club Brugge 1:4 | 6.81 | 5.13 | 1.48 | 1X | 2-1 | O | yes |
|
| 21:00 Al-Ahli Jeddah – Al-Khaleej 4:1 | 1.47 | 4.25 | 5.43 | 1 | 2-1 | O | no |
| 21:00 Al-Fateh Al-Ahsa – Al Kholood 2:5 | 1.85 | 3.50 | 3.66 | 1X | 2-1 | U | no |
|
| 21:00 Kaizer Chiefs – Lamontville Golden Arrows 1:0 | 1.42 | 3.72 | 7.95 | 1X | 2-0 | U | no |
| 21:00 Sekhukhune United – Stellenbosch 0:1 | 2.15 | 2.74 | 3.70 | 1X | 2-0 | U | no |
|
| 21:15 Bodo-Glimt – Manchester City 3:1 | 6.86 | 6.15 | 1.41 | 2 | 1-3 | O | yes |
|
| 23:15 Charlton Athletic – Derby County 1:2 | 2.59 | 2.99 | 2.84 | 1X | 2-0 | U | no |
| 23:15 Coventry City – Millwall 2:1 | 1.77 | 3.60 | 4.46 | 1 | 2-1 | U | no |
| 23:15 Ipswich Town – Bristol City 2:0 | 1.66 | 3.78 | 4.98 | X2 | 0-1 | U | no |
| 23:15 Oxford United – Queens Park Rangers 0:0 | 2.65 | 3.12 | 2.67 | 2X | 0-2 | U | no |
| 23:15 Preston North End – Hull City 0:3 | 2.16 | 3.30 | 3.32 | 1X | 1-0 | U | no |
| 23:15 Sheffield Wednesday – Birmingham City 0:2 | 6.51 | 4.20 | 1.48 | 1X | 3-0 | U | no |
| 23:15 Swansea City – Blackburn Rovers 3:1 | 2.00 | 3.26 | 3.84 | 2X | 0-2 | U | no |
| 23:15 West Bromwich Albion – Norwich City 0:5 | 1.95 | 3.52 | 3.69 | 1 | 2-0 | U | no |
|
| 23:15 Stevenage – Bolton Wanderers 0:0 | 3.32 | 3.32 | 2.15 | 1X | 2-1 | U | no |
|
| 23:15 Boreham Wood – Scunthorpe United 1:3 | 1.61 | 3.90 | 4.51 | 1 | 1-0 | U | yes |
| 23:15 Hartlepool United – Gateshead 2:1 | 1.45 | 4.40 | 5.48 | X2 | 0-1 | O | no |
| 23:15 Southend United – Eastleigh 4:1 | 1.32 | 4.55 | 8.20 | 1 | 1-0 | U | no |
| 23:15 Truro City – Brackley Town 3:3 | 2.34 | 2.96 | 2.99 | 1X | 2-1 | U | no |
| 23:15 Yeovil Town – Aldershot Town PP | 2.81 | 3.34 | 2.25 | 1X | 2-1 | U | no |
|
| 23:15 Alloa Athletic – Montrose 4:1 | 1.85 | 3.38 | 3.81 | 1X | 2-1 | U | no |
| 23:15 East Fife – Inverness 0:2 | 6.33 | 3.90 | 1.46 | 2 | 0-3 | U | no |
|
| 23:15 Livingston – St. Mirren 1:1 | 2.82 | 3.25 | 2.44 | 1X | 2-1 | U | no |
|
| 23:30 Wrexham – Leicester City 1:1 | 2.19 | 3.44 | 3.13 | 1X | 2-1 | U | no |
|
| 23:30 Copenhagen – Napoli 1:1 | 4.12 | 3.54 | 2.04 | 2 | 0-3 | U | yes |
| 23:30 Internazionale Milano – Arsenal 1:3 | 2.95 | 3.29 | 2.68 | 1X | 2-1 | U | no |
| 23:30 Olympiacos Piraeus – Bayer 04 Leverkusen 2:0 | 2.42 | 3.75 | 2.98 | 1X | 2-1 | U | no |
| 23:30 Real Madrid – AS Monaco 6:1 | 1.34 | 6.20 | 9.15 | 1 | 3-1 | O | no |
| 23:30 Sporting Clube de Portugal – Paris Saint-Germain 2:1 | 4.42 | 4.22 | 1.81 | 2 | 1-2 | O | yes |
| 23:30 Tottenham Hotspur – Borussia Dortmund 2:0 | 2.91 | 3.66 | 2.51 | 2X | 0-2 | U | no |
| 23:30 Villarreal – Ajax 1:2 | 1.43 | 5.38 | 7.60 | 1 | 2-1 | O | no |
