|
| 21:30 Burgos – Getafe 3:1 | 3.22 | 2.97 | 2.58 | 1X | 2-0 | U | no |
| 21:30 Ourense – Athletic Bilbao 0:0 | 7.60 | 4.20 | 1.50 | 2 | 0-3 | U | no |
|
| 23:30 Reading – Luton Town 3:2 | 2.76 | 3.34 | 2.44 | 1X | 2-1 | U | no |
|
| 23:30 Real Murcia – Real Betis 0:2 | 7.10 | 4.30 | 1.51 | 2 | 0-3 | U | no |
|
| 23:30 AC Omonia – Rakow Czestochowa 0:1 | 2.69 | 3.36 | 2.76 | 1X | 2-0 | U | no |
| 23:30 AC Sparta Prague – Aberdeen 3:0 | 1.18 | 7.80 | 17.00 | 1 | 2-1 | O | no |
| 23:30 AEK Athens – CS Universitatea Craiova 3:2 | 1.47 | 4.57 | 7.65 | 1 | 1-0 | U | no |
| 23:30 AEK Larnaca – Skendija 1:0 | 1.63 | 3.91 | 6.13 | 1 | 2-1 | O | no |
| 23:30 Crystal Palace – Kuopion Palloseura 2:2 | 1.26 | 6.51 | 11.50 | 1 | 3-1 | O | no |
| 23:30 Lausanne-Sport – Fiorentina 1:0 | 3.76 | 3.68 | 2.03 | 2 | 1-2 | U | yes |
| 23:30 Slovan Bratislava – Hacken 1:0 | 2.33 | 3.78 | 2.96 | 1X | 2-1 | U | no |
| 23:30 1. FSV Mainz 05 – Samsunspor 2:0 | 1.62 | 4.32 | 5.46 | 1 | 2-1 | O | no |
| 23:30 AZ Alkmaar – Jagiellonia Bialystok 0:0 | 1.59 | 4.36 | 5.77 | 1 | 2-1 | O | no |
| 23:30 Celje – Shelbourne 0:0 | 1.21 | 6.98 | 15.50 | 1 | 2-1 | O | no |
| 23:30 Dynamo Kyiv – Noah Yerevan 2:0 | 2.41 | 3.45 | 3.06 | 1 | 2-0 | U | no |
| 23:30 Legia Warsaw – Lincoln Red Imps 4:1 | 1.29 | 5.99 | 11.50 | 1 | 3-1 | O | no |
| 23:30 Rayo Vallecano – KF Drita 3:0 | 1.14 | 8.40 | 26.00 | 1 | 3-1 | O | no |
| 23:30 Shakhtar Donetsk – Rijeka 0:0 | 1.92 | 3.62 | 4.26 | 1 | 2-1 | O | no |
| 23:30 Shamrock Rovers – Hamrun Spartans 3:1 | 1.90 | 3.62 | 4.36 | 1 | 2-0 | U | no |
| 23:30 Sigma Olomouc – Lech Poznan 1:2 | 3.43 | 2.86 | 2.57 | 2X | 0-2 | U | no |
| 23:30 Strasbourg – Breidablik UBK 3:1 | 1.21 | 7.50 | 14.40 | 1 | 3-1 | O | no |
| 23:30 Zrinjski – Rapid Wien 1:1 | 1.94 | 3.68 | 4.12 | 2X | 0-2 | U | no |
