|
| 03:30 ABB – Gualberto Villarroel 0:0 | 2.01 | 3.58 | 3.28 | 2X | 1-2 | O | no |
|
| 04:30 Guadalajara – Tigres de la UANL 0:0 | 2.46 | 3.28 | 2.83 | 1X | 2-1 | U | no |
|
| 05:00 Real Salt Lake – Los Angeles 1:4 | 2.93 | 3.58 | 2.37 | 2X | 1-2 | U | no |
|
| 17:30 Modern Sport – ENPPI 2:2 | 2.26 | 2.84 | 3.48 | 2X | 0-2 | U | no |
| 17:30 Ismaily – Zamalek 0:2 | 8.25 | 3.82 | 1.43 | 2X | 0-2 | U | no |
|
| 18:00 Arda Kardzhali – CSKA Sofia 1:0 | 3.70 | 3.40 | 2.01 | 2X | 0-2 | U | no |
|
| 19:10 Al-Taawon – Ettifaq Dammam 4:1 | 2.36 | 3.35 | 2.72 | 1X | 1-0 | U | no |
| 19:10 Al Kholood – Damac 2:1 | 1.95 | 3.52 | 3.50 | 2X | 0-1 | U | no |
|
| 20:15 Club Brugge – AS Monaco 4:1 | 2.46 | 3.68 | 2.96 | 1X | 2-1 | O | no |
| 20:15 Copenhagen – Bayer 04 Leverkusen 2:2 | 3.12 | 3.56 | 2.41 | 1X | 2-1 | U | no |
|
| 20:30 Pyramids – ZED 1:0 | 1.42 | 3.90 | 8.25 | 2X | 0-2 | U | no |
| 20:30 Al Ittihad Alexandria – Kahrbaa Alasmalia 0:1 | 2.10 | 2.77 | 4.09 | 1X | 2-0 | U | no |
|
| 21:30 Neom SC – Al-Okhdood 1:0 | 1.45 | 4.30 | 6.24 | 1 | 1-0 | U | no |
|
| 22:30 Always Ready – Universitario de Vinto 5:1 | 1.19 | 6.20 | 12.00 | 1 | 2-1 | O | no |
|
| 22:30 Eintracht Frankfurt – Galatasaray 5:1 | 2.26 | 3.96 | 3.12 | 1X | 2-1 | O | yes |
| 22:30 Manchester City – Napoli 2:0 | 1.68 | 4.20 | 5.48 | 1 | 1-0 | U | no |
| 22:30 Newcastle United – Barcelona 1:2 | 2.60 | 3.79 | 2.72 | 1X | 2-1 | U | yes |
| 22:30 Sporting Clube de Portugal – Kairat 4:1 | 1.10 | 13.30 | 30.00 | 1 | 3-1 | O | no |
